Compositional knockoff filter for high‐dimensional regression analysis of microbiome data
نویسندگان
چکیده
منابع مشابه
Compositional Mediation Analysis for Microbiome Studies
Motivated by recent advances in causal inference on mediation analysis and problems in the analysis of metagenomic data, we consider the effect of a treatment on an outcome transmitted through microbes, or compositional mediators. Compositional and high dimensional natures of such mediators make the standard mediation analysis not directly applicable. In this paper, we propose a method for esti...
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In many applications, we need to study a linear regression model that consists of a response variable and a large number of potential explanatory variables and determine which variables are truly associated with the response. In 2015, Barber and Candès introduced a new variable selection procedure called the knockoff filter to control the false discovery rate (FDR) and proved that this method a...
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ژورنال
عنوان ژورنال: Biometrics
سال: 2020
ISSN: 0006-341X,1541-0420
DOI: 10.1111/biom.13336